The big Coronavirus thread

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Comments

  • DeVlaeminck
    DeVlaeminck Posts: 9,104
    Article in the Guardian that the former chair of the vaccine taskforce thinks we should move away from containing the virus to treating the vulnerable who catch it - even suggests ending the mass vaccination programme in its current form - in short treat it like flu.
    [Castle Donington Ladies FC - going up in '22]
  • surrey_commuter
    surrey_commuter Posts: 18,867
    Well I have tested positive and my most noticeable symptom is being very thirsty
  • First.Aspect
    First.Aspect Posts: 17,167
    Mad_Malx said:

    First.Aspect said:

    mully79 said:

    First.Aspect said:

    mully79 said:

    First.Aspect said:

    mully79 said:

    Ok, arguing that lockdowns is political took away the actual point of the graphs which are very interesting.

    Lateral flow tests are made by machines but pcr are a swab your nose then genetically sequence in a test tube whilst recording your name and address against the result.

    Theres no manufacturing of the PCR test.

    Except manufacturing of the reagents, vials and instrumentation.

    And the roads, and aquaducts and the wine....
    That is so stupid.
    Manufacturing a vial isnt manufacturing a test any more than a flour mill manufactures bread.
    You do know that they are both chromatographic methods, right? That they both use reagents, containers and dyes, only PCR tests use an awful lot more of all of these things?

    Perhaps you have the school chemistry lab in mind, with racks of test tubed being repeatedly washed with a bristle brush and re-used or something like that.

    Someone says his mate makes PCR tests so they cant possibly be used to collect everyones genetic code.
    I'm calling BS as they're a test in a lab so there is no manufactured kit and you guys are arguing about the word manufactured. Lets move on now.
    You haven't got a clue have you?

    The point, that everyone who hasn't lost the will to live already got, is that a PCR test includes everything that a lateral flow test includes, and censored loads more.

    Not sure what your point is, tbh.
    That isn’t true. LFT measures expression of viral encoded proteins (ie the virus is replicating), pcr measures whether there is any Covid-19 RNA fragments (that the PCR primers target). It doesn’t tell you if there is viable virus, but LFT does (fairly well). That’s why you can be PCR positive long after infection has been cleared, it takes longer to clear the debris.
    Yeah I have a chemistry PhD, ta. I was referring to the "not manufactured" point that's all.
  • First.Aspect
    First.Aspect Posts: 17,167
    Mad_Malx said:

    As someone who has actually done (many) PCR tests for other targets -
    1. They do not gene sequence, but are often used as part of a sequencing protocol (because they amplify target sequences to provide sufficient material to sequence.
    2. They are not chromatographic techniques (but chromotography is sometimes used afterwards to confirm the amplified target)
    3. You could take the samples people send in to gene profile them if you wanted.
    4. The ‘manufactured’ comment is bizarre.
    5. It doesn’t need mechanical steps, it can all be done in one “tube” once extracted from the sample you send in by an automated process.

    Electrophoresis is a chromatographic method.
  • rick_chasey
    rick_chasey Posts: 75,661
    surrey_commuter said:

    Well I have tested positive and my most noticeable symptom is being very thirsty

    Ah sorry to hear that. Fingers crossed that’s all it is
    _
  • Mad_Malx
    Mad_Malx Posts: 5,183
    First.Aspect said:

    Mad_Malx said:

    As someone who has actually done (many) PCR tests for other targets -
    1. They do not gene sequence, but are often used as part of a sequencing protocol (because they amplify target sequences to provide sufficient material to sequence.
    2. They are not chromatographic techniques (but chromotography is sometimes used afterwards to confirm the amplified target)
    3. You could take the samples people send in to gene profile them if you wanted.
    4. The ‘manufactured’ comment is bizarre.
    5. It doesn’t need mechanical steps, it can all be done in one “tube” once extracted from the sample you send in by an automated process.

    Electrophoresis is a chromatographic method.
    PCR in itself doesn’t involve electrophoresis. A lot of high throughput screening uses Lightcycler or similar technology which measures fluorescent base incorporation without running a gel. As I said, chromotography might be used as a further confirmatory step.

    Your other point understood now.
  • kingstonian
    kingstonian Posts: 2,847
    surrey_commuter said:

    Well I have tested positive and my most noticeable symptom is being very thirsty


    If that’s the only symptom, happy days ! Hope you shift it soon.
  • First.Aspect
    First.Aspect Posts: 17,167
    Mad_Malx said:

    First.Aspect said:

    Mad_Malx said:

    As someone who has actually done (many) PCR tests for other targets -
    1. They do not gene sequence, but are often used as part of a sequencing protocol (because they amplify target sequences to provide sufficient material to sequence.
    2. They are not chromatographic techniques (but chromotography is sometimes used afterwards to confirm the amplified target)
    3. You could take the samples people send in to gene profile them if you wanted.
    4. The ‘manufactured’ comment is bizarre.
    5. It doesn’t need mechanical steps, it can all be done in one “tube” once extracted from the sample you send in by an automated process.

    Electrophoresis is a chromatographic method.
    PCR in itself doesn’t involve electrophoresis. A lot of high throughput screening uses Lightcycler or similar technology which measures fluorescent base incorporation without running a gel. As I said, chromotography might be used as a further confirmatory step.

    Your other point understood now.
    Right, got it now.
  • rjsterry
    rjsterry Posts: 29,551
    mully79 said:

    Ok, arguing that lockdowns is political took away the actual point of the graphs which are very interesting.

    Lateral flow tests are made by machines but pcr are a swab your nose then genetically sequence in a test tube whilst recording your name and address against the result.

    Theres no manufacturing of the PCR test.

    The f***ing idiocy of this post.
    1985 Mercian King of Mercia - work in progress (Hah! Who am I kidding?)
    Pinnacle Monzonite

    Part of the anti-growth coalition
  • kingstongraham
    kingstongraham Posts: 28,152
    If they anonymised the PCR tests it would get rid of this conspiracy theory. Potential downside - might make it a bit trickier to let people know the result.
  • Pross
    Pross Posts: 43,463
    kingstongraham said:

    If they anonymised the PCR tests it would get rid of this conspiracy theory. Potential downside - might make it a bit trickier to let people know the result.

    The lab in Birmingham tried this approach a few months ago (including my test).
  • Jezyboy
    Jezyboy Posts: 3,605
    kingstongraham said:

    If they anonymised the PCR tests it would get rid of this conspiracy theory. Potential downside - might make it a bit trickier to let people know the result.

    If you already beleive in the conspiracy, why would you beleive that the anonymised info was truly anonymised.
  • darkhairedlord
    darkhairedlord Posts: 7,180
    Jezyboy said:

    kingstongraham said:

    If they anonymised the PCR tests it would get rid of this conspiracy theory. Potential downside - might make it a bit trickier to let people know the result.

    If you already beleive in the conspiracy, why would you beleive that the anonymised info was truly anonymised.
    Don't they just sample your DNA, bin the results, and sell your name to a health insurance database?
  • veronese68
    veronese68 Posts: 27,814
    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.
    Kinesis Pro6
    Marin Nail Trail
    Cotic Solaris
  • kingstongraham
    kingstongraham Posts: 28,152
    Jezyboy said:

    kingstongraham said:

    If they anonymised the PCR tests it would get rid of this conspiracy theory. Potential downside - might make it a bit trickier to let people know the result.

    If you already beleive in the conspiracy, why would you beleive that the anonymised info was truly anonymised.
    Good point, they might use your dna to find out who you are.
  • First.Aspect
    First.Aspect Posts: 17,167
    And yet ancestry.com do a booming trade....
  • Stevo_666
    Stevo_666 Posts: 61,398
    veronese68 said:

    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.

    We ordered some kits on the NHS website last week and got them delivered 3 days later. That was 2 separate orders, one for me and one for junior so there doesn't seem to be a shortage.
    "I spent most of my money on birds, booze and fast cars: the rest of it I just squandered." [George Best]
  • pblakeney
    pblakeney Posts: 27,327
    First.Aspect said:

    And yet ancestry.com do a booming trade....

    "I don't want them to know who I am, where I am, or what I'm doing."
    Posts regularly on FB/Twitter/Whatsapp...
    The above may be fact, or fiction, I may be serious, I may be jesting.
    I am not sure. You have no chance.
    Veronese68 wrote:
    PB is the most sensible person on here.
  • sungod
    sungod Posts: 17,347
    Stevo_666 said:

    veronese68 said:

    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.

    We ordered some kits on the NHS website last week and got them delivered 3 days later. That was 2 separate orders, one for me and one for junior so there doesn't seem to be a shortage.
    there certainly has been either a shortage or a distribution problem or both

    we tried 10-15 times over the last week or so, the website always said none available, over the same period there've been consistent "no tests in stock" signs in a couple of pharmacies i go past, plenty of news reports of the same

    today they are available, presumably they restocked and/or demand no longer exceeds distribution capacity
    my bike - faster than god's and twice as shiny
  • Stevo_666
    Stevo_666 Posts: 61,398
    edited January 2022
    sungod said:

    Stevo_666 said:

    veronese68 said:

    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.

    We ordered some kits on the NHS website last week and got them delivered 3 days later. That was 2 separate orders, one for me and one for junior so there doesn't seem to be a shortage.
    there certainly has been either a shortage or a distribution problem or both

    we tried 10-15 times over the last week or so, the website always said none available, over the same period there've been consistent "no tests in stock" signs in a couple of pharmacies i go past, plenty of news reports of the same

    today they are available, presumably they restocked and/or demand no longer exceeds distribution capacity
    All I can say is that our orders were both fulfilled as normal and in line with the 3 working working day delivery timescale. No idea why you had problems but could be timing?
    "I spent most of my money on birds, booze and fast cars: the rest of it I just squandered." [George Best]
  • surrey_commuter
    surrey_commuter Posts: 18,867
    sungod said:

    Stevo_666 said:

    veronese68 said:

    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.

    We ordered some kits on the NHS website last week and got them delivered 3 days later. That was 2 separate orders, one for me and one for junior so there doesn't seem to be a shortage.
    there certainly has been either a shortage or a distribution problem or both

    we tried 10-15 times over the last week or so, the website always said none available, over the same period there've been consistent "no tests in stock" signs in a couple of pharmacies i go past, plenty of news reports of the same

    today they are available, presumably they restocked and/or demand no longer exceeds distribution capacity
    it is hit and miss so best to randomise your online attempts
  • DeVlaeminck
    DeVlaeminck Posts: 9,104
    First.Aspect said:

    And yet ancestry.com do a booming trade....

    Ancestry.com.gov.uk
    [Castle Donington Ladies FC - going up in '22]
  • kingstongraham
    kingstongraham Posts: 28,152
    Stevo_666 said:

    sungod said:

    Stevo_666 said:

    veronese68 said:

    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.

    We ordered some kits on the NHS website last week and got them delivered 3 days later. That was 2 separate orders, one for me and one for junior so there doesn't seem to be a shortage.
    there certainly has been either a shortage or a distribution problem or both

    we tried 10-15 times over the last week or so, the website always said none available, over the same period there've been consistent "no tests in stock" signs in a couple of pharmacies i go past, plenty of news reports of the same

    today they are available, presumably they restocked and/or demand no longer exceeds distribution capacity
    All I can say is that our orders were both fulfilled as normal and in line with the 3 working working day delivery timescale. No idea why you had problems but could be timing?
    It's been pretty widely reported that there have been intermittent issues with availability over the last few weeks, so not really a surprise.
  • Stevo_666
    Stevo_666 Posts: 61,398
    kingstongraham said:

    Stevo_666 said:

    sungod said:

    Stevo_666 said:

    veronese68 said:

    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.

    We ordered some kits on the NHS website last week and got them delivered 3 days later. That was 2 separate orders, one for me and one for junior so there doesn't seem to be a shortage.
    there certainly has been either a shortage or a distribution problem or both

    we tried 10-15 times over the last week or so, the website always said none available, over the same period there've been consistent "no tests in stock" signs in a couple of pharmacies i go past, plenty of news reports of the same

    today they are available, presumably they restocked and/or demand no longer exceeds distribution capacity
    All I can say is that our orders were both fulfilled as normal and in line with the 3 working working day delivery timescale. No idea why you had problems but could be timing?
    It's been pretty widely reported that there have been intermittent issues with availability over the last few weeks, so not really a surprise.
    Not now it would appear.
    "I spent most of my money on birds, booze and fast cars: the rest of it I just squandered." [George Best]
  • Mad_Malx
    Mad_Malx Posts: 5,183
    Stevo_666 said:

    sungod said:

    Stevo_666 said:

    veronese68 said:

    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.

    We ordered some kits on the NHS website last week and got them delivered 3 days later. That was 2 separate orders, one for me and one for junior so there doesn't seem to be a shortage.
    there certainly has been either a shortage or a distribution problem or both

    we tried 10-15 times over the last week or so, the website always said none available, over the same period there've been consistent "no tests in stock" signs in a couple of pharmacies i go past, plenty of news reports of the same

    today they are available, presumably they restocked and/or demand no longer exceeds distribution capacity
    All I can say is that our orders were both fulfilled as normal and in line with the 3 working working day delivery timescale. No idea why you had problems but could be timing?
    The system checks for blue genes to decide if you are eligible.
  • surrey_commuter
    surrey_commuter Posts: 18,867
    Stevo_666 said:

    kingstongraham said:

    Stevo_666 said:

    sungod said:

    Stevo_666 said:

    veronese68 said:

    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.

    We ordered some kits on the NHS website last week and got them delivered 3 days later. That was 2 separate orders, one for me and one for junior so there doesn't seem to be a shortage.
    there certainly has been either a shortage or a distribution problem or both

    we tried 10-15 times over the last week or so, the website always said none available, over the same period there've been consistent "no tests in stock" signs in a couple of pharmacies i go past, plenty of news reports of the same

    today they are available, presumably they restocked and/or demand no longer exceeds distribution capacity
    All I can say is that our orders were both fulfilled as normal and in line with the 3 working working day delivery timescale. No idea why you had problems but could be timing?
    It's been pretty widely reported that there have been intermittent issues with availability over the last few weeks, so not really a surprise.
    Not now it would appear.
    yes, now
  • kingstongraham
    kingstongraham Posts: 28,152
    Stevo_666 said:

    kingstongraham said:

    Stevo_666 said:

    sungod said:

    Stevo_666 said:

    veronese68 said:

    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.

    We ordered some kits on the NHS website last week and got them delivered 3 days later. That was 2 separate orders, one for me and one for junior so there doesn't seem to be a shortage.
    there certainly has been either a shortage or a distribution problem or both

    we tried 10-15 times over the last week or so, the website always said none available, over the same period there've been consistent "no tests in stock" signs in a couple of pharmacies i go past, plenty of news reports of the same

    today they are available, presumably they restocked and/or demand no longer exceeds distribution capacity
    All I can say is that our orders were both fulfilled as normal and in line with the 3 working working day delivery timescale. No idea why you had problems but could be timing?
    It's been pretty widely reported that there have been intermittent issues with availability over the last few weeks, so not really a surprise.
    Not now it would appear.
    I would say maybe in the last week or so from posts above.
  • Stevo_666
    Stevo_666 Posts: 61,398
    edited January 2022
    surrey_commuter said:

    Stevo_666 said:

    kingstongraham said:

    Stevo_666 said:

    sungod said:

    Stevo_666 said:

    veronese68 said:

    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.

    We ordered some kits on the NHS website last week and got them delivered 3 days later. That was 2 separate orders, one for me and one for junior so there doesn't seem to be a shortage.
    there certainly has been either a shortage or a distribution problem or both

    we tried 10-15 times over the last week or so, the website always said none available, over the same period there've been consistent "no tests in stock" signs in a couple of pharmacies i go past, plenty of news reports of the same

    today they are available, presumably they restocked and/or demand no longer exceeds distribution capacity
    All I can say is that our orders were both fulfilled as normal and in line with the 3 working working day delivery timescale. No idea why you had problems but could be timing?
    It's been pretty widely reported that there have been intermittent issues with availability over the last few weeks, so not really a surprise.
    Not now it would appear.
    yes, now
    Not to me it doesn't.

    See what happens if you order now on the NHS.
    "I spent most of my money on birds, booze and fast cars: the rest of it I just squandered." [George Best]
  • rick_chasey
    rick_chasey Posts: 75,661
    Is there ever an argument on here where Stevo doesn't do the "I'm alright, Jack" bit?

    _
  • surrey_commuter
    surrey_commuter Posts: 18,867
    Stevo_666 said:

    surrey_commuter said:

    Stevo_666 said:

    kingstongraham said:

    Stevo_666 said:

    sungod said:

    Stevo_666 said:

    veronese68 said:

    Lad has just tested positive, I was at work when I found out so came home immediately to do a test myself. Wife and I are clear at the moment.
    Managed to pick up some LFT tests on the way back, for anyone in the Kingston area you can pick them up in the market square.
    The last page of this thread certainly illustrates the point nicely that there are several people on here that know what they are talking about, and some others.

    We ordered some kits on the NHS website last week and got them delivered 3 days later. That was 2 separate orders, one for me and one for junior so there doesn't seem to be a shortage.
    there certainly has been either a shortage or a distribution problem or both

    we tried 10-15 times over the last week or so, the website always said none available, over the same period there've been consistent "no tests in stock" signs in a couple of pharmacies i go past, plenty of news reports of the same

    today they are available, presumably they restocked and/or demand no longer exceeds distribution capacity
    All I can say is that our orders were both fulfilled as normal and in line with the 3 working working day delivery timescale. No idea why you had problems but could be timing?
    It's been pretty widely reported that there have been intermittent issues with availability over the last few weeks, so not really a surprise.
    Not now it would appear.
    yes, now
    Not to me it doesn't.

    See what happen if you order now on the NHS.
    Friday - missus ordered some
    Saturday - I couldn't get in
    Sunday - couldn't get in
    Monday - couldn't be bothered as going nowhere

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