The big Coronavirus thread

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  • DeVlaeminck
    DeVlaeminck Posts: 9,110
    johngti said:

    **** it - youngest daughter just tested positive.

    So has Mrs GTi. Negative this morning so her parents came over as planned. Positive tonight so tomorrow’s off and I’ve told them to do daily lateral flow tests for the next few days, as will me and the kids while the wife moves into the conservatory. Fun times 😶
    Ive been in the kitchen with a window open for the last 5 days or so avoiding the wife - she's sleeping on the sofa bed - I'm thinking it may have made more sense not to bother and just catch the virus but have a more normal Xmas in the house at least.
    [Castle Donington Ladies FC - going up in '22]
  • tailwindhome
    tailwindhome Posts: 19,470

    johngti said:

    **** it - youngest daughter just tested positive.

    So has Mrs GTi. Negative this morning so her parents came over as planned. Positive tonight so tomorrow’s off and I’ve told them to do daily lateral flow tests for the next few days, as will me and the kids while the wife moves into the conservatory. Fun times 😶
    Ive been in the kitchen with a window open for the last 5 days or so avoiding the wife - she's sleeping on the sofa bed - I'm thinking it may have made more sense not to bother and just catch the virus but have a more normal Xmas in the house at least.
    Can understand this point of view. We're simultaneously glad we don't have it and sorry we're aren't getting it over with. Had we all had it, daughter wouldn't have spent Xmas Day in her room

    The concern is the seeming random nature of - outside of obvious vulnerabilities - who has no symptoms and who goes to ICU.
    “New York has the haircuts, London has the trousers, but Belfast has the reason!
  • tailwindhome
    tailwindhome Posts: 19,470
    edited December 2021
    ...
    “New York has the haircuts, London has the trousers, but Belfast has the reason!
  • mully79
    mully79 Posts: 904
    edited December 2021
    My parents now both have it despite being triple jabbed.
    I sit here thinking the chances of ending up in ICU are so small its not worth worrying about. Then again, OH has won her second £500 jackpot in a month and the odds of that are nearly impossible :D
  • veronese68
    veronese68 Posts: 27,894
    It seems the booster doesn't give protection for very long, how long ago did they have it? Given that it seems the vaccinations keep symptoms to a minimum I believe they are still worth having.
    Presumably new vaccines will come out to follow the new varieties of virus, let's hope the drug companies can keep up with the rate of change.
  • Timing is everything, eh? Tasmania has had 18 months of zero cases, and only re-opened cross-border travel the week before Christmas, a plan made before Omicron had appeared. There's now a few hundred cases here and accumulating quickly.

    We're not even eligible for a booster yet, another month still.

    In the meantime, OH is booked for next major operation in 2 weeks and is understandably nervous about it. Half expecting the whole procedure to be postponed by the surgeon, but won't know for another week and a bit. No idea yet what the hospital protocols will be, but I'm dreading the possibility I won't be allowed in to visit.

    Open One+ BMC TE29 Seven 622SL On One Scandal Cervelo RS
  • Stevo_666
    Stevo_666 Posts: 61,923
    edited December 2021
    Wrong thread
    "I spent most of my money on birds, booze and fast cars: the rest of it I just squandered." [George Best]
  • mully79
    mully79 Posts: 904

    It seems the booster doesn't give protection for very long, how long ago did they have it? Given that it seems the vaccinations keep symptoms to a minimum I believe they are still worth having.
    Presumably new vaccines will come out to follow the new varieties of virus, let's hope the drug companies can keep up with the rate of change.

    Booster was a month or two ago. They're in their 70's.
  • veronese68
    veronese68 Posts: 27,894
    mully79 said:

    It seems the booster doesn't give protection for very long, how long ago did they have it? Given that it seems the vaccinations keep symptoms to a minimum I believe they are still worth having.
    Presumably new vaccines will come out to follow the new varieties of virus, let's hope the drug companies can keep up with the rate of change.

    Booster was a month or two ago. They're in their 70's.
    Hope reports are true and they don't get it too badly.
  • mully79
    mully79 Posts: 904

    mully79 said:

    It seems the booster doesn't give protection for very long, how long ago did they have it? Given that it seems the vaccinations keep symptoms to a minimum I believe they are still worth having.
    Presumably new vaccines will come out to follow the new varieties of virus, let's hope the drug companies can keep up with the rate of change.

    Booster was a month or two ago. They're in their 70's.
    Hope reports are true and they don't get it too badly.
    Cheers, so far, mum has a sore throat and cold but is improving. Dad felt like death xmas eve night but felt far better by xmas day.
  • briantrumpet
    briantrumpet Posts: 20,910
    mully79 said:

    mully79 said:

    It seems the booster doesn't give protection for very long, how long ago did they have it? Given that it seems the vaccinations keep symptoms to a minimum I believe they are still worth having.
    Presumably new vaccines will come out to follow the new varieties of virus, let's hope the drug companies can keep up with the rate of change.

    Booster was a month or two ago. They're in their 70's.
    Hope reports are true and they don't get it too badly.
    Cheers, so far, mum has a sore throat and cold but is improving. Dad felt like death xmas eve night but felt far better by xmas day.

    Seems that omicron is approx max 5-day thing from initial infection to cleared in most (vaccinated) people. Also good news.
  • rjsterry
    rjsterry Posts: 29,877
    edited December 2021
    johngti said:

    **** it - youngest daughter just tested positive.

    So has Mrs GTi. Negative this morning so her parents came over as planned. Positive tonight so tomorrow’s off and I’ve told them to do daily lateral flow tests for the next few days, as will me and the kids while the wife moves into the conservatory. Fun times 😶
    Sorry to hear that (and DeV). Not sure we could realistically isolate one of us in our house, so it would be just sitting it out and hoping we could get a home delivery slot.
    1985 Mercian King of Mercia - work in progress (Hah! Who am I kidding?)
    Pinnacle Monzonite

    Part of the anti-growth coalition
  • DeVlaeminck
    DeVlaeminck Posts: 9,110

    mully79 said:

    mully79 said:

    It seems the booster doesn't give protection for very long, how long ago did they have it? Given that it seems the vaccinations keep symptoms to a minimum I believe they are still worth having.
    Presumably new vaccines will come out to follow the new varieties of virus, let's hope the drug companies can keep up with the rate of change.

    Booster was a month or two ago. They're in their 70's.
    Hope reports are true and they don't get it too badly.
    Cheers, so far, mum has a sore throat and cold but is improving. Dad felt like death xmas eve night but felt far better by xmas day.

    Seems that omicron is approx max 5-day thing from initial infection to cleared in most (vaccinated) people. Also good news.
    My wife has had it longer than that and is still testing positive and has (admittedly fairly mild) symptoms - pretty sure it is omicron too as it's presented as a classic cold rather than a cough or any loss of taste.
    [Castle Donington Ladies FC - going up in '22]
  • TheBigBean
    TheBigBean Posts: 22,075
    With the caveat that this is published in Telegraph, this article is quite interesting as it suggests the AZ vaccine may offer better long term protection.

    https://archive.ph/9Acfd
  • briantrumpet
    briantrumpet Posts: 20,910

    With the caveat that this is published in Telegraph, this article is quite interesting as it suggests the AZ vaccine may offer better long term protection.

    https://archive.ph/9Acfd


    I think I might have read similar elsewhere, although it does seem to be conjecture, albeit plausible (if one knows nothing about T cells or, well, anything to do with the science of it all).
  • With the caveat that this is published in Telegraph, this article is quite interesting as it suggests the AZ vaccine may offer better long term protection.

    https://archive.ph/9Acfd

    Is it true that most vulnerable people were given the AZ vaccine? All the olds I know had Pfizer across the board, and us on the next rung down had AZ.

    Also we were pretty early on boosters for the old - before Omicron came along - which must have made a difference.
  • briantrumpet
    briantrumpet Posts: 20,910

    With the caveat that this is published in Telegraph, this article is quite interesting as it suggests the AZ vaccine may offer better long term protection.

    https://archive.ph/9Acfd

    Is it true that most vulnerable people were given the AZ vaccine? All the olds I know had Pfizer across the board, and us on the next rung down had AZ.

    Also we were pretty early on boosters for the old - before Omicron came along - which must have made a difference.

    Fair point, but maybe it's less important whether it was the vulnerable or not, just that overall big use of AZ has somehow had an effect by dulling the worst of the omicron wave in the general (vaccinated) population. Yet another reason why the massive amounts of data coming in must be (and will continue to be, for years in retrospect, I guess) both fascinating and useful.
  • sungod
    sungod Posts: 17,495

    With the caveat that this is published in Telegraph, this article is quite interesting as it suggests the AZ vaccine may offer better long term protection.

    https://archive.ph/9Acfd

    there's other research suggesting the exact opposite, for instance...
    https://khub.net/documents/135939561/430986542/Effectiveness+of+COVID-19+vaccines+against+Omicron+variant+of+concern.pdf/f423c9f4-91cb-0274-c8c5-70e8fad50074

    tbh it's too early to say either way, the long term damage/death rates vs. infections are what really matter, not simply infections
    my bike - faster than god's and twice as shiny
  • Mad_Malx
    Mad_Malx Posts: 5,188
    edited December 2021
    The T cell response is important in immune memory (and other stuff).
    Antibody levels are important in mopping up the infection, but drop over time (I think the half life is about 3 months).

    It's likely that that the different vaccines have different effects on the magnitude and duration of antibody and T- cell responses. There is a fair consensus that Pfizer & Moderna give better a better antibody response. *If * , as suggested, there is an enhanced T cell response with AZ, but antibody levels have dropped, then you will likely still get mild disease but the antibody levels will be boosted again very rapidly so you can clear the infection more rapidly.

    In the USA, the Johnson & Johnson vax was rolled out as one shot effective. This was never looking very likely from a scientific viewpoint, but probably helped uptake (of one shot) in a perhaps more sceptical population.

  • Mad_Malx
    Mad_Malx Posts: 5,188

    With the caveat that this is published in Telegraph, this article is quite interesting as it suggests the AZ vaccine may offer better long term protection.

    https://archive.ph/9Acfd

    Is it true that most vulnerable people were given the AZ vaccine? All the olds I know had Pfizer across the board, and us on the next rung down had AZ.
    I think so - my recollection is that, while Pfizer was rolled out first, the bulk supply was initially AZ because of easier storage and more availability. So prob depends on wherabout on the vunerability scale you look.
  • veronese68
    veronese68 Posts: 27,894
    I think MM has a point, I was fairly early, mid-feb for my first, and Ive had Pfizer for all of my jabs
  • briantrumpet
    briantrumpet Posts: 20,910
    It cheers me up that I can check on the health status of the one person who lives in the entire commune of Rochefourchat by looking at the national map of communes.



    tl;dr - he hasn't got covid.

    On the other hand, the national map does suggest that my theory (schools being closed/masked, and the pass sanitaire) about why France was doing better than the UK might have been flawed. 500 more people were hospitalised yesterday, after nearly 3000 over the previous three days. Hmm.

  • Mad_Malx said:

    The T cell response is important in immune memory (and other stuff).
    Antibody levels are important in mopping up the infection, but drop over time (I think the half life is about 3 months).

    It's likely that that the different vaccines have different effects on the magnitude and duration of antibody and T- cell responses. There is a fair consensus that Pfizer & Moderna give better a better antibody response. *If * , as suggested, there is an enhanced T cell response with AZ, but antibody levels have dropped, then you will likely still get mild disease but the antibody levels will be boosted again very rapidly so you can clear the infection more rapidly.

    In the USA, the Johnson & Johnson vax was rolled out as one shot effective. This was never looking very likely from a scientific viewpoint, but probably helped uptake (of one shot) in a perhaps more sceptical population.

    Quite right. Cellular response is king. The virus may be able to evade antibodies, but if it ever evades the cellular response, it really becomes a very serious problem.
  • kingstonian
    kingstonian Posts: 2,847

    It cheers me up that I can check on the health status of the one person who lives in the entire commune of Rochefourchat by looking at the national map of communes.



    tl;dr - he hasn't got covid.

    On the other hand, the national map does suggest that my theory (schools being closed/masked, and the pass sanitaire) about why France was doing better than the UK might have been flawed. 500 more people were hospitalised yesterday, after nearly 3000 over the previous three days. Hmm.


    What was your theory?
  • briantrumpet
    briantrumpet Posts: 20,910

    It cheers me up that I can check on the health status of the one person who lives in the entire commune of Rochefourchat by looking at the national map of communes.



    tl;dr - he hasn't got covid.

    On the other hand, the national map does suggest that my theory (schools being closed/masked, and the pass sanitaire) about why France was doing better than the UK might have been flawed. 500 more people were hospitalised yesterday, after nearly 3000 over the previous three days. Hmm.


    What was your theory?
    As per this post... that they were doing better because of the measures cited. Load of bollix, obvs, in retrospect.
  • orraloon
    orraloon Posts: 13,297
    When did France introduce pass sanitaire? Wasn't in place when I was in the France Belgian border area 4 weeks ago. Belgium did have their 'Covid ticket' operating plus face coverings indoors.
  • briantrumpet
    briantrumpet Posts: 20,910
    orraloon said:

    When did France introduce pass sanitaire? Wasn't in place when I was in the France Belgian border area 4 weeks ago. Belgium did have their 'Covid ticket' operating plus face coverings indoors.

    Been there for furriners to enter cafés and suchlike since last August, and for the locals since July, I think. Quite heavy penalties for businesses who don't enforce it via the phone app.
  • orraloon
    orraloon Posts: 13,297

    orraloon said:

    When did France introduce pass sanitaire? Wasn't in place when I was in the France Belgian border area 4 weeks ago. Belgium did have their 'Covid ticket' operating plus face coverings indoors.

    Been there for furriners to enter cafés and suchlike since last August, and for the locals since July, I think. Quite heavy penalties for businesses who don't enforce it via the phone app.
    Oops. Looks like department Nord population and establishments weren't following da roolz then. No checking or QR scanning. Unlike a few hundred metres across the line on the map. Was a bit weird in the last place we had lunch on the Sunday, Belgian countryside just across border with couple French towns nearby. We scanned in as the norm, wore masks when moving around as did the Belgians. But couple of big family groups of French, one there must have been about 20 adults and kids running about, sans masks.

    Is 59 a hotspot?
  • briantrumpet
    briantrumpet Posts: 20,910
    orraloon said:

    orraloon said:

    When did France introduce pass sanitaire? Wasn't in place when I was in the France Belgian border area 4 weeks ago. Belgium did have their 'Covid ticket' operating plus face coverings indoors.

    Been there for furriners to enter cafés and suchlike since last August, and for the locals since July, I think. Quite heavy penalties for businesses who don't enforce it via the phone app.
    Oops. Looks like department Nord population and establishments weren't following da roolz then. No checking or QR scanning. Unlike a few hundred metres across the line on the map. Was a bit weird in the last place we had lunch on the Sunday, Belgian countryside just across border with couple French towns nearby. We scanned in as the norm, wore masks when moving around as did the Belgians. But couple of big family groups of French, one there must have been about 20 adults and kids running about, sans masks.

    Is 59 a hotspot?

    No, not at the mo - about 527/100k, compared with double that SE of Lyon and down the Rhône corridor.
  • kingstonian
    kingstonian Posts: 2,847

    It cheers me up that I can check on the health status of the one person who lives in the entire commune of Rochefourchat by looking at the national map of communes.



    tl;dr - he hasn't got covid.

    On the other hand, the national map does suggest that my theory (schools being closed/masked, and the pass sanitaire) about why France was doing better than the UK might have been flawed. 500 more people were hospitalised yesterday, after nearly 3000 over the previous three days. Hmm.


    What was your theory?
    As per this post... that they were doing better because of the measures cited. Load of bollix, obvs, in retrospect.

    Ah, sorry, I clearly didn’t read your post properly. I also think testing hasn’t been quite as prevalent in France as has been the case in the U.K. and that’s left a lot of non-symptomatic infections undetected.