Does Di2 need indexing?

in Workshop
Hi all.
Asking this as I thought it didn't but recently I've noticed on my canyon aeroad that when in big ring and moving through gears on cassette it starts "clicking"
It's as if it's trying to get into the gear but can't, havnt had this before untill recently after I cleaned bike and wondering if there a way to sort this with di2?
Any help be great cheers
Asking this as I thought it didn't but recently I've noticed on my canyon aeroad that when in big ring and moving through gears on cassette it starts "clicking"
It's as if it's trying to get into the gear but can't, havnt had this before untill recently after I cleaned bike and wondering if there a way to sort this with di2?
Any help be great cheers
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Posts
https://d104voyrhl640v.cloudfront.net/2019/08/ultegra-R8050-manual.pdf
(Same procedure for all series AFAIK)
Pages 128 onwards....