Will this wheel fit?

I have a Cube Reaction bike which is fitted with a X12 thru axle on the rear wheel. I need to change this wheel and am finding that wheels with thru axles are really expensive.
Is it possible to fit a wheel with a standard QR skewer onto a frame which was originally designed for a thru axle?
Is it possible to fit a wheel with a standard QR skewer onto a frame which was originally designed for a thru axle?
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Rear mech has nothing to do with the axle, and what can't you get off, the rear mech, wheel, mech hanger?
Not 100% sure but reckon the answer is no since qr axles require an open drop out.