Swapping wheelsets

Im thinking of buying a second set of wheels so I can swap between a road setup and a gravel/cx/light off-road setup. Is there any reason I can't just have a second set of wheels with the different tyres and an identical cassette on to quickly change my bike from one thing to the other?
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If they are disc braked the same can apply to the brake calliper alignment.
retired 9.6kg Carrera Kraken
The Carrera Hardtail combined thread - come on all you Carrera's!
The Sons Scott Genius RC20 build
You could probably do the same with cassettes - but you'd need some thin spacers to get it accurate. Once done you'd be down to a few seconds work each change.
Ignoring the chain/cassette thing.
Beginning to think of and when I get a disc all-rounder I'm going to be better off with just one decent wheel set and some versatile tyres, like the Hutch sector 28s or similar. I'm a road rider basically, but occasionally it'd be nice to do some (very) light off-road or gravel.
My sons bike is a canti braked road bike with good tyre clearance so I'll maybe do the swapping thing with his if the cassette and chain issue isn't really a thing.
In practice this is seldom a problem in my experience. Changing a wheel is a 30 second job and the indexing is almost always OK. What is often necessary is to adjust the brakes as different rim widths come into play. Changing tyres is much more of a hassle.......