quick question on rear drop outs

My frame has quite long horizontal rear drop outs. How far up them should I position the wheels - as far up/in as they can go or just in the middle. About to fit a new chain so position will need to stay the same from now on....
Thks
Thks
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The old fork adjusters were good for sorting out ideal position. If you don't have provision for them it is down to trial and error - if you do have provision for them get some!