Beginners attempting Holyhead to Swansea in 3 days.Possible?

Myself and 5 other friends are thinking about biking from Holyhead to Swansea for sports relief in March. We all are very young, sporty and fit people, but with no biking experience as such. I am in process of planning the route this is it so far:
Holyhead - Bangor - Porthmadog - Dolgellau - Machynlleth - Aberystwyth - Llanrhystud - Aberaeron - Llanbedr - Talley - Llandeilo - Ammanford - Pontarddulais - Swansea
or if this is impossible then there is a route from my home town Shrewsbury to the coast 117 miles away Aberystwth.
So I was just looking for advice on whether this would be possible for us, and if we would be able to do it on our mountain bikes? or would we have to look into renting/borrowing road bikes? any helpful ideas or advice would be very helpful!
Holyhead - Bangor - Porthmadog - Dolgellau - Machynlleth - Aberystwyth - Llanrhystud - Aberaeron - Llanbedr - Talley - Llandeilo - Ammanford - Pontarddulais - Swansea
or if this is impossible then there is a route from my home town Shrewsbury to the coast 117 miles away Aberystwth.
So I was just looking for advice on whether this would be possible for us, and if we would be able to do it on our mountain bikes? or would we have to look into renting/borrowing road bikes? any helpful ideas or advice would be very helpful!
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Try plotting your planned route here: http://www.mapmyride.com/ which will give you a better idea of the ups & downs you may face.
The other thing to consider is whether you're planning to have all of your travel kit on your bikes with you, or whether you will have a 'support vehicle' (wife for instance) who will be able to take spare clothes/ bike parts (tubes/tyres/tools etc.) from location to location.
...and a few training rides wouldn't go amiss.
Regarding the route I'd suggest you consider how much A-road riding you want to do, as the traffic could be a bit scary - or at the least not fun. Bangor-Porthmadog-Dogleggy is all trunk road and not relaxing. If you have plenty of time you could look at using parts of Sustrans' Route 8, Lon Las Cymru. On Anglesey you can now use the A5, as the fast traffic crosses the island on the dual carriageway A55. Also bear in mind that March is not always a kind month weather-wise, and it might be less of a chore riding from South to North (providing the wind is in the typical South-Westerley direction).
Being of a cautious nature I'd try something shorter for your first big event (or use it as trial run for the big one). Routes from Shrewsbury to Aber include NCR 81. See the Sustrans Wales routes page for more.
If you want to talk offline send me a PM, I live in Shrewsbury too and know parts of Mid-Wales quite well.
...or it will be three long days in the saddle.
If the aber ride goes well we are going to do the Holyhead - Cardiff one because it will be a big acheivment. But thanks for all your help, we have invested in a padded seat and some decent clothes even after our short ride round the lake we realised it was worth it!
After the shorts, if you don't already have them your best investment would be some slick tyres. Makes a massive difference on the road.
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